Wei-Hsiang Chang

• Ph. D　Environmental and Occupational Health of National Cheng Kung University, Taiwan
• M.S Occupational Safety and Health of Kaohsiung Medical University, Taiwan
• B.S Public Health of Fu Jen Catholic University, Taiwan

• Associate professor – Department of Food Safety / Hygiene and Risk Management, College of Medicine, National Cheng Kung University, Taiwan 2024/08~Present
• Adjunct Associate professor – Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Taiwan 2024/08~Present
• Adjunct Associate Research Fellow – Research Center of Environmental Trace Toxic Substances, National Cheng Kung University 2024/08~Present
• Director – Ultra-Trace Analytical Laboratory, Research Center of Environmental Trace Toxic Substances 2021/8~Present
• Lecture (Risk Assessment) – National Environmental Research Academy, Ministry of Environment 2019~Present
• Lecture (Toxic Chemicals) – National Environmental Research Academy, Ministry of Environment 2019~Present

• Assistant Professor – Department of Food Safety / Hygiene and Risk Management, College of Medicine, National Cheng Kung University, Taiwan 2020/2 ~ 2024/7
• Adjunct Assistant professor – Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Taiwan 2023/2~2024/7
• Assistant Research Fellow – Research Center of Environmental Trace Toxic Substances, National Cheng Kung University 2017/2~2021/1
• Visiting Scientist – Joint Institute for Food Safety and Applied Nutrition and University of Maryland 2015

Academic Journal Editor

• Guest Editor of TOXICS (Impact Factor: 3.784) 2021~2022
• Guest Editor of Atmosphere (Impact Factor: 2.5) 2023~2024

Academic Journal Editor

• Guest Editor of TOXICS (Impact Factor: 3.784) 2021~2022
• Guest Editor of Atmosphere (Impact Factor: 2.5) 2023~2024

Position in Academic Organizations

• Director – Taiwan Society of Indoor Environmental Quality 2023/05~Present
• Deputy secretary general – Taiwan Society of Indoor Environmental Quality (TSIEQ) 2018/5~2024/4
• Metabolomics Society, Member
• International Society of Exposure Science (ISES), Member
• International Society for Environmental Epidemiology (ISEE), Member
• International Symposium on Halogenated Persistent Organic Pollutants (Dioxin 20XX), Member
• Taiwan Society of Indoor Environmental Quality (TSIEQ), Member
• International Association for Food Protection (IAFP), Member

• Award of Young Researcher Excellence in Research, Medical College, National Cheng Kung University (2024)
• Award of FutureTech, National Science and Technology Council (2024)
• Kung-Pei Chen Memorial Award of Excellence in Research (Advice PhD student) (2023)
• Award of Excellence in Research, NCKU hospital Cheng-Hsing Medical Foundation (2023)
• Award of Global ILSI Federation Scholars Travel (IFST) (2022)
• Grand Award of Global ILSI Food Safety and Risk Analysis (2015)

Book/ Invited Article

1. 李俊璋、張偉翔，2023，當代公共衛生學叢書：環境與職業衛生－毒性及關注化學物質管理。財團法人陳拱北預防醫學基金會，ISBN：9786269783410。
2. 張偉翔，2024，「永遠化學品－全氟及多氟烷基物質(PFAS)」來襲！！ 我該關心飲用水安全嗎？。消費者報導。
3. 張偉翔，2023，雙酚A 不可不知的事。消費者報導，2023年08月508期。
4. 張偉翔，2021，室內空氣健康學－遠離廚房空污。衛生福利部國民健康署。

Refereed Paper

1. Quang-Oai Lu, Wei-Hsiang Chang, Hone-Jay Chu, Ching-Chang Lee. 2024 October. Enhancing Indoor PM2.5 Predictions Based on Land Use and Indoor Environmental Factors by Applying Machine Learning and Spatial Modeling Approaches. Environmental Pollution. 318, 120893. (SCI IF=7.6, rank=37/358=10.3% in Environmental Sciences, JCR 2023) https://doi.org/10.1016/j.envpol.2024.125093
2. Kuan-Hung Liu, Wei-Hsiang Chang, Edward Chia-Cheng Lai, Pei-Chen Tsai, Bin Hsu, Yu-Hsuan Yang, Wei-Ren Lin, Tzu-Shan Huang, Fang-Yi Su, Jung-Hsien Chiang, Chung-Yi Li, Yau-Sheng Tsai, Junne-Ming Sung. 2024 January. Ambient Temperature and the Occurrence of Intradialytic Hypotension in Patients Receiving Hemodialysis. Clinical Kidney Journal, 17(1), sfad304 (SCI IF=3.9, rank=18/126=14.3% in Urology & Nephrology, JCR 2023) https://doi.org/10.1093/ckj/sfad304
3. Yu-Jung Lin, Wei-Hsiang Chang, Pao-Lin Kuo, Hsin-Chang Chen, Wan-Ting Chang, Po-Chin Huang. 2023 December. Oxidative/nitrosative stress increased the risk of recurrent pregnancy loss–Taiwan Recurrent Pregnancy Loss and Environmental Study (TREPLES). Redox Biology. 68, 102940 (SCI IF=10.7, rank=17/313=5.43% in Biochemistry & Molecular biology, JCR 2023) https://doi.org/10.1016/j.redox.2023.102940
4. Quang-Oai Lu, Chien-Cheng Jung, How-Ran Chao, Pei-Shih Chen, Chia-Wei Lee, Quynh Thi Phuong Tran, Jyun-Yi Ciou, Wei-Hsiang Chang (Corresponding author). 2023 March. Investigating the associations between organophosphate flame retardants (OPFRs) and fine particles in paired indoor and outdoor air: A probabilistic prediction model for deriving OPFRs in indoor environments. Environment International. 174, 107871 (SCI IF=10.3, rank=21/358=5.86% in Environmental Sciences, JCR 2023) https://doi.org/10.1016/j.envint.2023.107871
5. Tsung‑Ho Ying, Chun‑Jui Huang, Chia‑Jung Hsieh, Pei‑Ju Wu, Chang‑Ching Yeh, Ping‑Kun Hung, Wei‑Hsiang Chang, Meng‑Hsing Wu, Hsin Hung, Jung‑Wei Chang, Chen‑Tai Wang, Rachelle D. Arcega. Trias Mahmudiono, Ching‑Chang Lee, Hsiu‑Ling Chen. 2023 March. Potential factors associated with the blood metal concentrations of reproductive‑age women in Taiwan. Exposure and Health. 16, 17-86 (SCI IF=4.5 rank=20/127=15.7% in Water resources, JCR 2023) https://doi.org/10.1007/s12403-023-00541-4
6. Ching-Chang Lee, Bo-Lun Lin, Yi-Wen Huang, Ning-Syuan Hsu, Wei-Hsiang Chang (Corresponding author). 2023 March. Simultaneous determination of 24 congeners of 2- and 3‑monochloropropanediol esters and 7 congeners of glycidyl esters using direct multi-residue analytical LC-MS/MS methods in various food matrices. Journal of Food and Drug Analysis. 31(1), 55-72 (SCI IF=2.6, rank=85/173=49.1% in Food Science and Technology, JCR 2023) https://doi.org/10.38212/2224-6614.3442
7. Quang-Oai Lu, Chien-Cheng Jung, Yu-Hsuan Liu, Wei-HsiangChang (Corresponding author). 2023 February. Seasonal and source characteristics of organophosphorus flame retardants in air and house dust in Taiwan residential microenvironments: Implications for young children’s exposure and risk assessment using a probabilistic approach. Environmental Pollution. 318, 120893. (SCI IF=7.6, rank=37/358=10.3% in Environmental Sciences, JCR 2023) https://doi.org/10.1016/j.envpol.2022.120893
8. Rachelle D. Arcega, Rong-Jane Chen, Pei-Shan Chih, Yi-Hsuan Huang, Wei-Hsiang Chang, Ting-Khai Kong, Ching-Chang Lee, Trias Mahmudiono, Chun-Chih Tsui, Wen-Che Hou, Hsin-Ta Hsueh, Hsiu-Ling Chen. 2022 December. Toxicity prediction: An application of alternative testing and computational toxicology in contaminated groundwater sites in Taiwan. Journal of Environmental Management. 328, 116982 (SCI IF=8.0, rank=34/358=9.49% in Environmental Sciences, JCR 2023) https://doi.org/10.1016/j.jenvman.2022.116982
9. Wei-Hsiang Chang, Quang-Oai Lu, Hsiu-Ling Chen, Ning-Syuan Hsu, Ching-Chang Lee. 2022 August. Insights into the long-term fates and impacts of polybrominated diphenyl ethers in sediment samples in Taiwan: The national project for background monitoring of the environmental distribution of chemical substances (BMECs). Environmental Pollution. 306, 119417. (SCI IF=7.6, rank=37/358=10.3% in Environmental Sciences, JCR 2023) 　https://doi.org/10.1016/j.envpol.2022.119417
10. Wei-Hsiang Chang, Pei-Hsuan Chen, Samuel Herianto, Hsiu-Ling Chen, Ching-Chang Lee. 2022 August. Aggregating exposures and toxicity equivalence approach into an integrated probabilistic dietary risk assessment for perchlorate, nitrate, and thiocyanate: Results from the National food monitoring study and National Food Consumption Database. Environmental Research. 211, 112989. (SCI IF=7.7, rank=36/358=10.0% in Environmental Sciences, JCR 2023) https://doi.org/10.1016/j.envres.2022.112989
11. Rachelle D. Arcega, Chih-Yao Hou, Shu-Chen Hsu, Chia-Min Lin, Wei-Hsiang Chang, Hsiu-Ling Chen. 2022 July. Reduction of pesticide residues in Chrysanthemum morifolium by nonthermal plasma-activated water and impact on its quality. Journal of Hazardous Materials. 434, 128610. (SCI IF=12.2, rank=12/358=3.35% in Environmental Sciences, JCR 2023) https://doi.org/10.1016/j.jhazmat.2022.128610
12. Yung-Chieh Lin, Wei-Hsiang Chang, Tsun-Ching Li, Osuke Iwata, Hsiu-Ling Chen. 2022 June. Health risk of infants exposed to lead and mercury through breastfeeding. Exposure and Health. 15, 255–267 (SCI IF=4.5 rank=20/127=15.7% in Water resources, JCR 2023) https://doi.org/10.1007/s12403-022-00485-1
13. Huey-Jen Su, Chien-Cheng Jung, Jui-Hsin Wang, Nai-Tzu Chen, Wei-Hsiang Chang. 2022 May. Estimations of infiltration factors of diurnal PM2.5 and heavy metals in children’s bedrooms. Indoor Air. 32 (5), e13037 (SCI IF=4.3, rank=47/403=11.7% in Public, Environmental & Occupational Health, JCR 2023) https://doi.org/10.1111/ina.13037
14. Junne-Ming Sung, Wei-Hsiang Chang, Kuan-Hung Liu, Chung Yu Chen, Trias Mahmudiono, Wan-Ru Wang, Ho-Chi Hsu, Zhen-Yi Li, Hsiu-Ling Chen. 2022 January. The effect of co-exposure to glyphosate, cadmium, and arsenic on chronic kidney disease. Exposure and Health. 14, 779–789. (SCI IF=4.5 rank=20/127=15.7% in Water resources, JCR 2023) https://doi.org/10.1007/s12403-021-00451-3
15. Chung-Yu Chen, Yu-Hsuan Liu, Chia-Hui Chieh, Wei-Hsiang Chang (Corresponding author). 2021 December. Fast and environment-Friendly GC-MS method for eleven organophosphorus flame retardants in indoor air, dust, and skin wipes. Toxics. 9(12), 350 (SCI IF=3.9, rank=120/358 =33.5% in Environmental Sciences, JCR 2023) https://doi.org/10.3390/toxics9120350
16. Chien-Cheng Jung, Jui-Hsin Wang, Wei-Hsiang Chang, Chung-Yu Chen. 2021 November. Metal concentration, source, and health risk assessment of PM₅ in children’s bedrooms: Rural versus urban areas. Atmospheric Environment. 264, 118701 (SCI IF=4.2, rank=88/359 =24.5% in Environmental Sciences, JCR 2022). https://doi.org/10.1016/j.atmosenv.2021.118701
17. I-Cheng Lu, How-Ran Chao, Wan-Nurdiyana-Wan Mansor, Chun-Wei Peng, Yi-Chyun Hsu, Tai-Yi Yu, Wei-Hsiang Chang, Lung-Ming Fu. 2021 October. Levels of Phthalates, Bisphenol-A, Nonylphenol, and Microplastics in Fish in the Estuaries of Northern Taiwan and the Impact on Human Health. Toxics. 9(10), 246. (SCI IF=3.9, rank=120/358 =33.5% in Environmental Sciences, JCR 2023) https://doi.org/10.3390/toxics9100246
18. Bing-Jyh Lu,Tzu-Che Lin, How-Ran Chao, Cheng-Hsian Tsai, Jian-He Lu, Ming-Hsien Tsai, Ching-Tzu Chang, Hao Hsieh, I-Cheng Lu, Rachelle D. Arcega, Wei-Hsiang Chang, Hsiu-Ling Chen, Wan Nurdiyana Wan Mansor, Ying-Chieh Lee. 2021 October. The Impact of Air or Nitrogen Non-Thermal Plasma on Variations of Natural Bioactive Compounds in Djulis (Chenopodium formosanum Koidz.) Seed and the Potential Effects for Human Health. Atmosphere. 12(11), 1375. (SCI IF=2.5, rank=203/359 =56.5% in Environmental Sciences, JCR 2023) https://doi.org/10.3390/atmos12111375
19. Wei-Hsiang Chang, Wei-Chun Chou, Alexander Waits, Kai-Wei Liao, Pao-Lin Kuo, Po-Chin Huang. 2021 September. Cumulative risk assessment of phthalates exposure for recurrent pregnancy loss in reproductive-aged women population using multiple hazard indices approaches. Environment International. 154, 106657. (SCI IF=10.3, rank=21/358=5.86% in Environmental Sciences, JCR 2023) https://doi.org/10.1016/j.envint.2021.106657
20. Wei-Hsiang Chang, Samuel Herianto, Ching-Chang Lee, Hsin Hung, Hsiu-Ling Chen. 2021. September. The effects of phthalate ester exposure on human health: A review. Science of the Total Environment. 786, 14371. (SCI IF=8.2, rank=31/358=8.66% in Environmental Sciences, JCR 2023) https://doi.org/10.1016/j.scitotenv.2021.147371
21. Kai-Wei Liao, Wei-Hsiang Chang, Wei-Chun Chou, Han-Bin Huang, Alexander Waits, Pau-Chung Chen, Po-Chin Huang. 2021 June. Human biomonitoring reference values and characteristics of Phthalate exposure in the general population of Taiwan: Taiwan Environmental Survey for Toxicants 2013-2016. International Journal of Hygiene and Environmental Health. 235, 113769. (SCI IF=4.5, rank=43/403=10.6% in Public, Environmental, & Occupational Health, JCR 2023) https://doi.org/10.1016/j.ijheh.2021.113769
22. Po-Chin Huang, Pao-Lin Kuo, Wei-Hsiang Chang, Shu-Fang Shih, Wan-Ting Chang, Ching-Chang Lee. 2021 April. Prenatal Phthalates Exposure and Cord Thyroid Hormones: A Birth Cohort Study in Southern Taiwan. International Journal of Environmental Research and Public Health. 18, 4323. (SCI IF=4.614, rank=43/403=33.8% in Public, Environmental, & Occupational Health, JCR 2021) https://doi.org/10.3390/ijerph18084323
23. Wen-Lii Huang, Wei-Hsiang Chang, Shu-Fen Cheng, Huai-Yuan Li, Hsiu-Ling Chen. 2021 April. Potential Risk of Consuming Vegetables Planted in Soil with Copper and Cadmium and the Influence on Vegetable Antioxidant Activity. Applied Sciences-Basel. 11(9), 3761. (SCI IF=2.5, rank=44/179=24.6% in Engineering, Multidisciplinary, JCR 2023) https://doi.org/10.3390/app11093761
24. Ching-Chang Lee, Wei-Hsiang Chang (Equal contribution to first author), Chung-Feng Hung, Hsiu-Ling Chen. 2020 October. Fish consumption is an indicator of exposure to non-dioxin like polychlorinated biphenyls in cumulative risk assessments based on a probabilistic and sensitive approach. Environmental Pollution. 268, 115732. (SCI IF=7.6, rank=37/358=10.3% in Environmental Sciences, JCR 2023) https://doi.org/10.1016/j.envpol.2020.115732
25. Po-Chin Huang, Wei-Hsiang Chang, Ming-Tsang Wu, Mei-Lien Chen, I-Jen Wang, Shu-Fang Shih, Chao A Hsiung, Kai-Wei Liao. 2020 September. Characterization of phthalate exposure in relation to serum thyroid and growth hormones, and estimated daily intake levels in children exposed to phthalate-tainted products: A longitudinal cohort study. Environmental Pollution. 264, 114648. (SCI IF=7.6, rank=37/358=10.3% in Environmental Sciences, JCR 2023) https://doi.org/10.1016/j.envpol.2020.114648
26. Alexander Waits, Hsin-Chang Chen, Pao-Lin Kuo, Chih-Wen Wang, Han-Bin Huang, Wei-Hsiang Chang, Shu-Fang Shih, Po-Chin Huang. 2020 Sept. Urinary phthalate metabolites are associated with biomarkers of DNA damage and lipid peroxidation in pregnant women – Tainan Birth Cohort Study (TBCS). Environmental Research. 188, 109863. (SCI IF=7.7, rank=36/358=10.0% in Environmental Sciences, JCR 2023) https://doi.org/10.1016/j.envres.2020.109863
27. Wei-Hsiang Chang, Hsiu-Ling Chen, Ching-Chang Lee. 2020 Aug. Dietary exposure assessment to perchlorate in the Taiwanese population: A risk assessment based on the probabilistic approach. Environmental Pollution. 267, 115486. (SCI IF=7.6, rank=37/358=10.3% in Environmental Sciences, JCR 2023) https://doi.org/10.1016/j.envpol.2020.115486
28. Ching-Chang Lee, Wei-Hsiang Chang, Hsin-Tang Lin, Jung-Wei Chang. 2020 Aug. Spatiotemporal Patterns of Polychlorinated Dibenzo-p-dioxins and Dibenzofurans and Dioxin-like Polychlorinated Biphenyls in Foodstuffs in Air Quality Regions in Taiwan. Journal of Food and Drug Analysis. 28, 375-398. (SCI IF=2.6, rank=85/173=49.1% in Food Science and Technology, JCR 2023) https://doi.org/10.38212/2224-6614.1216
29. Ching-Chang Lee, Wei-Hsiang Chang, Hsiu-Ling Chen. 2019 Jun. Dietary exposure and risk assessment of exposure to hexabromocyclododecanes in a Taiwan population. Environmental Pollution 249: 728-734. (SCI IF=7.6, rank=37/358=10.3% in Environmental Sciences, JCR 2023) https://doi.org/10.1016/j.envpol.2019.03.040
30. Wei-Hsiang Chang, Yuh-Shyan Tsai, Jia-Yu Wang, Hsiu-Ling Chen, Wen-Hong Yang, Ching-Chang Lee. 2019 May. Sex hormones and oxidative stress mediated phthalate-induced effects in prostatic enlargement. Environment International 126:184-192. (SCI IF=10.3, rank=21/358=5.86% in Environmental Sciences, JCR 2023) https://doi.org/10.1016/j.envint.2019.02.006
31. Wei-Hsiang Chang, Ching-Chang Lee, Yun-He Yen, Hsiu-Ling Chen. 2019 Dec. Oxidative damage in patients with benign prostatic hyperplasia and prostate cancer co-exposed to phthalates and to trace elements. Environment International 121:1179-1184. (SCI IF=10.3, rank=21/358=5.86% in Environmental Sciences, JCR 2023) https://doi.org/10.1016/j.envint.2018.10.034
32. Wei-Hsiang Chang, Shou-Chun Liu, Hsiu-Ling Chen, Ching-Chang Lee. 2019 Jan. Dietary intake of 4-nonylphenol and bisphenol A in Taiwanese population: Integrated risk assessment based on probabilistic and sensitive approach. Environmental Pollution 244: 143-152. (SCI IF=7.6, rank=37/358=10.3% in Environmental Sciences, JCR 2023) https://doi.org/10.1016/j.envpol.2018.10.040
33. Wei-Hsiang Chang, Meng-Hsing Wu, Hsien-An Pan, Pao-Lin Guo, Ching-Chang Lee. 2017 Apr. Semen quality and insulin-like factor 3: association with biomarkers in adult males exposed to phthalates. Chemosphere 173:594-602. (SCI IF=8.1, rank=32/358=8.94% in Environmental Sciences, JCR 2023) https://doi.org/10.1016/j.chemosphere.2017.01.056
34. Wei-Hsiang Chang, Sih-Syuan Li, Meng-Hsing Wu, Hsien-An Pan, Ching-Chang Lee. 2015 Nov. Phthalates might interfere with testicular function by reducing testosterone and insulin-like factor 3 levels. Human Reproduction 30:2658-2670. (SCI IF=6.0, rank=6/136=4.41% in Obstetrics & Gynecology, JCR 2023) https://doi.org/10.1093/humrep/dev225

Conference Paper

1. Wei-Hsiang Chang and Tzu-An Liu. Monitoring of 16 Organophosphate Flame Retardants in Foodstuffs and Dietary Exposure Risk Assessment for the Taiwanese Population. 44th International Symposium on Halogenated Persistent Organic Pollutants (POPs), Singapore, Singapore, September 29- October 4, 2024.
2. Ching Chang Lee, Pin Ting Liu, Wei Hsiang Chang. Investigation and dietary intake risk assessment of poly- and perfluoroalkyl substances in foods. 44th International Symposium on Halogenated Persistent Organic Pollutants (POPs), Singapore, Singapore, September 29- October 4, 2024.
3. Wei-Hsiang Chang, Hao-Lun Chang, Pi-Shan Sung. Nutrimetabolomics and dietary biomarker of diet associated with Alzheimer’s disease. Metabolomics 2024, Osaka, Japan, June 16-20, 2024.
4. Wei-Jeng Chao, Wei-Hsiang Chang, Yung-Chieh Lin. Human breast milk metabolome: exploring associations the key markers with gestational age and early postnatal development. Metabolomics 2024, Osaka, Japan, June 16-20, 2024.
5. Pei-Yu Wu and Wei-Hsiang Chan An exposome-wide approach of organophosphate flame retardants in the Taiwanese population: Parent-child pairs interaction and potential health risk. 35th Annual Conference of the International Society for Environmental Epidemiology, Kaohsiung, Taiwan, September 17-21, 2023.
6. Wei-Hsiang Chang, Hsiu-Ling Chen, Ching-Chang Lee. Multimedia Environmental Endocrine-Disrupting Chemicals and Food Safety: Implications for Mixture Risk Assessment using a probabilistic approach. 35th Annual Conference of the International Society for Environmental Epidemiology, Kaohsiung, Taiwan, September 17-21, 2023.
7. Tzu-Ling Chu, Ching-Chang Lee, Wei-Hsiang Chang, Yu-Ting Wang. The mediating role of phthalate metabolites on dietary inflammatory index and prostatic enlargement in Taiwanese adults. 35th Annual Conference of the International Society for Environmental Epidemiology, Kaohsiung, Taiwan, September 17-21, 2023.
8. Tomohiko Yanagawa, Wei-Hsiang Chang, Wei-Hsuan Hsu, Ching-Chang Lee. Occurrence and accumulation of microplastics contamination in freshwater fishes from natural and farmed sources in Taiwan. 35th Annual Conference of the International Society for Environmental Epidemiology, Kaohsiung, Taiwan, September 17-21, 2023.
9. Wei-Hsiang Chang. Characterizing and risk assessment of human exposure to Organophosphorus Flame Retardants: Merging exposure markers of multiple pathway and biomonitoring data. 43rd International Symposium on Halogenated Persistent Organic Pollutants (POPs), Maastricht, Netherlands, September 10-14, 2023.
10. Wei-Hsiang Chang. Human breast milk metabolome, environment and infant development. Metabolomics 2023, Ontario, Canada, June 18-22, 2023.
11. Hao-Lun Chang, Wei-Hsiang Chang, Tzu-Ling Chu, Yu-Ting Wang. Nutritional metabolome relationships provide improving insights into dietary intake and Alzheimer’s disease. Metabolomics 2023, Ontario, Canada, June 18-22, 2023.
12. Wei-Hsiang Chang, Ching-Chang Lee, Chia-Hui Chieh, Yu-Hsuan Liu, and Yu-Ting Wang. Characterization of organophosphate flame retardants associated with decoration materials and electrical appliances in indoor environment. 11th international conference on indoor air quality, ventilation & energy conservation in buildings, Tokyo, Japan, May 20-23, 2023.
13. Ching-Chang Lee, Wei-Hsiang Chang, Hsiu-Ling Chen, Ken-Hui Chang, Chao-heng Tseng. Improvement efficiency of indoor air quality for elementary schools using FVAS and other management strategies in Taiwan. 11th international conference on indoor air quality, ventilation & energy conservation in buildings, Tokyo, Japan, May 20-23, 2023.
14. Jia-Li Ke,Wei-Hsiang Chang, Ching-Chang Lee. Development of an isotope-labeled method for determination of polychlorinated naphthalenes in sediment and fish using gas chromatography–triple quadrupole tandem mass spectrometry. 2023 conference on Environmental Analytical Chemistry, Taoyuan, Taiwan, May 17-18, 2023.
15. Che-Wei Chang, Wei-Hsiang Chang, Ching-Chang Lee. The Investigation of Short Chain Chlorinated Paraffins in Foods and Health Risk Assessment. 2023 conference on Environmental Analytical Chemistry, Taoyuan, Taiwan, May 17-18, 2023.
16. Chiu-Chin Chen, Wei-Hsiang Chang, Hsiu-Ling Chang, Ching-Chang Lee. Non-target analysis of intentionally and non-intentionally added substances from virgin and recycled paper/paperboard for food contact materials. 2023 conference on Environmental Analytical Chemistry, Taoyuan, Taiwan, May 17-18, 2023.
17. Tomohiko Yanagawa, Wei-Hsiang Chang, Wei-Hsuan Hsu. Microplastic consumption and accumulation of wild fish in 15 principal rivers of Taiwan. 2022 Taiwan Public Health Joint Annual Conference, Taipei, Taiwan, October 14-16, 2022.
18. Wei-Hsiang Chang and Ching-Chang Lee. Probabilistic Estimation of the Aggregate Dietary Exposure of Taiwanese Populations to 2-/3- Monochloropropanediol esters and Glycidyl esters and Health Risk Assessment: the implications for food safety management strategies. ILSI 2022 Annual Meeting. Brussels, Belgium, June 27-30, 2022.
19. Wei-Hsiang Chang, Chia-Hui Chieh, Yu-Hsuan Liu. Study on exposure assessment of organophosphate flame retardants in indoor and outdoor environment for adults and children. Indoor Air 2022. Kuopio, Finland, June 12-16, 2022.
20. Wei-Hsiang Chang, Pei-Hsuan Chen, Samuel Herianto, Hsiu-Ling Chen, Ching-Chang Lee. Probabilistic and cumulative risk assessment of perchlorate, nitrate and thiocyanate in foods: a toxicity equivalence approach. EFSA ONE – Health, Environment, Society – Conference 2022. Brussels, Belgium, June 21-24, 2022.
21. Wei-Hsiang Chang, Tzu-An Liu. Characterizing food consumption associated with the targeted metabolites of organophosphate flame retardants in children and their caregivers. International Conference: A human exposome approach on industrial contaminated sites and health concerns. Limasso, Cyprus, Nov 29-30, 2021.
22. Chia-Hui Chieh, Wei-Hsiang Chang, Ching-Chang Lee. Exposure characteristics of organophosphate flame retardants via multiple exposures routes in children. 2021 Conference on Indoor Environmental Quality Health , Infection Prevention and Intelligent Living in Asia. Tainan, Taiwan, June 3-4, 2021. [Excellent paper award ]
23. Jyun-Yi Ciou, Chien-Cheng Jung, Wei-Hsiang Chang, Ching-Chang Lee. Investigating associations between building characteristics, PM2.5 and organophosphate flame retardants in Tainan households. 2021 Conference on Indoor Environmental Quality Health , Infection Prevention and Intelligent Living in Asia. Tainan, Taiwan, June 3-4, 2021.
24. Yi-Chin Li, Wei-Hsiang Chang, Ching-Chang Lee. Concentration distribution of phthalate esters in processed foods and fresh foods in Taiwan and source discussion. 2021 conference on Environmental Analytical Chemistry. Taoyuan, Taiwan, June 29-30, 2021.
25. I Lan, Wei-Hsiang Chang, Ching-Chang Lee. Risk Assessment and Management of Dietary Exposure to Phthalate Esters for Taiwanese. 2021 conference on Environmental Analytical Chemistry. Taoyuan, Taiwan, June 29-30, 2021.
26. Yu-Hsuan Liu, Wei-Hsiang Chang, Ching-Chang Lee. Occurrences and characterization of organophosphate flame retardants in indoor air and dust: a multi‐location households study. Indoor Air 2020. Seoul, Korea, July 20-24, 2020.
27. Chia-Hui Chieh, Yu-Hsuan Liu, Wei-Hsiang Chang, Ching-Chang Lee. Associations of organophosphate flame retardants levels in indoor air and house dust with seasonal variation and environmental factors in the households. 2020 Public Health Joint Annual Conference. Taipei, Taiwan, October 17-18, 2020.
28. Ya-Hsuan Tasi, Yu-Wen Chang, Wei-Hsiang Chang, Meng-Xing Wu, Zhen-Xiang You, Ching-Chang Lee. The effects of maternal exposure to thyroid disrupting substances on the growth and development of newborns. 2020 Public Health Joint Annual Conference. Taipei, Taiwan, October 17-18, 2020.
29. Wei-Hsiang Chang, Hsiu-Ling Chen, Ching-Chang Lee. Sex hormones and oxidative stress promote the development of prostatic hyperplasia with phthalate exposures. 2020 Public Health Joint Annual Conference. Taipei, Taiwan, October 17-18, 2020.
30. Mei-Chen Cheng, Yu-Wen Chang, Wei-Hsiang Chang, Meng-Hsing Wu, Chen-Hsiang Yu, Ching-Chang Lee. Potential Sources of thyroid disrupting chemicals and its effects of the neonatal development. 2019 Public Health Joint Annual Conference. Taipei, Taiwan, October 17-18, 2019.
31. Wei-Hsiang Chang and Ching-Chang Lee. Dietary exposure to dioxin and dioxin-like compounds in Taiwanese populations with diversified diets. 39th International Symposium on Halogenated Persistent Organic Pollutants – DIOXIN2019, Kyoto, Japan, August 25-30, 2019.
32. Jung-Wei Chang, Ching-Chang Lee, Chiao-Yi Cheng, Wei-Hsiang Chang. Temporal trends and spatial distribution of　PCDD/Fs and dioxin-like PCBs in Taiwan foodstuffs. 39th International Symposium on Halogenated Persistent Organic Pollutants – DIOXIN2019, Kyoto, Japan, August 25-30, 2019.
33. Wei-Hsiang Chang, Chia-Ding Liao, Guan-Liang Wu, Chung-Feng Hung, Ching-Chang Lee. Dietary exposure and human risk assessment of phthalate esters in processed food. 2019 Conference for Food Hygiene and Inspection Technology, Chiayi, Taiwan, August 21-22, 2019.
34. Ching-Chang Lee, Wei-Hsiang Chang and Guan-Liang Wu. Occurrence and profiles of phthalates in processed food from Taiwan and their implications for human exposure. International Association for Food Protection 2019 Annual Meeting (IAFP 2019), Louisville, Kentucky, United State, July 21-24, 2019.
35. Wei-Hsiang Chang and Ching-Chang Lee. Estimated daily intake and cumulative risk assessment of perchlorate via diverse foods for Taiwanese populations. International Association for Food Protection 2019 Annual Meeting (IAFP 2019), Louisville, Kentucky, United State, July 21-24, 2019.
36. Wei-Hsiang Chang, Hsiu-Ling Chen, Shou-Chun Liu, Ching Chang Lee. Background Monitoring of Nonylphenol and Bisphenol a Levels in Foods Around Taiwan and BPA Migrating Test from Packaging Materials of Coffee Products. International Association for Food Protection 2018 Annual Meeting (IAFP 2018), Salt Lake City, Utah, United State, July 8-11, 2018.
37. Ching-Chang Lee and Wei-Hsiang Chang. Occurrence of Perchlorate in Bottled water, Beverage and Tea from Taiwan Market by High Performance Liquid Chromatography–Tandem Mass Spectrometry. International Association for Food Protection 2018 Annual Meeting (IAFP 2018), Salt Lake City, Utah, United State, July 8-11, 2018.
38. Hsiu-Ling Chen, Ching Chang Lee, Wei-Hsiang Chang. Integrated Risk Assessment of nonylphenol and bisphenol A through dietary intake in Taiwan population. International Association for Food Protection 2018 Annual Meeting (IAFP 2018), Salt Lake City, Utah, United State, July 8-11, 2018.
39. Yu-Ping Fu, Wei-Hsiang Chang, Meng-Hsing Wu, Horng-Yih Ou, Ching-Chang Lee. Urinary perchlorate and thiocyanate are associated with thyroid function in pregnant women. Conference of International Society for Environmental Epidemiology and International Society of Exposure Science－Asia Chapter 2018 (ISEE/ES AC 2018), Taipei, Taiwan, June 21-25, 2018.
40. Yu-Wen Chang, Wei-Hsiang Chang, Ching-Chang Lee. Polybrominated diphenyl ethers in sediment from Taiwan principal rivers: levels, spatial and seasonal distribution and influence factors. 2018 conference on Environmental Analytical Chemistry. Taoyuan, Taiwan, May 3-4, 2018.

Our lab comprises postdoctoral researchers, research assistants with a master’s degree, graduate students, and undergraduate project students. We welcome students interested in interdisciplinary studies on emerging contaminants, metabolomics, nutrition intake, and precision health to join our team

• PhD student Quang-Oai Lu (Co-advice with Prof. Ching-Chang Lee) Kung-Pei Chen Memorial Award of Excellence in Research (2023)
• Master student Chiu-Chin Chen Judges’Award The 10th International Congress of Asian Society of Toxicology (ASIATOX-X） (2023)
• Master student Chia-Hui Chieh (Co-advice with Prof. Ching-Chang Lee) Outstanding Research Paper Award International Conference on Environmental Air Pollution, Indoor Environmental Quality Health and Intelligent Living in Asia (2020)

• 2024 Wei-Jeng Chao. Associations of human breast milk metabolome and exposome on infant growth. Department of Food Safety / Hygiene and Risk Management, College of Medicine, National Cheng Kung University. Master.
• 2024 Pei-Yu Wu. Pregnancy exposure to legacy and emerging phthalate and dietary iodine intake: Implications for thyroid hormone homeostasis and birth outcomes. Department of Food Safety / Hygiene and Risk Management, College of Medicine, National Cheng Kung University. Master.
• 2024 Le Ngoc Phu. Developing a clinical practice approach to address nutrition and protein-energy wasting in patients with end-stage renal disease using a multi-diet index approach. Department of Food Safety / Hygiene and Risk Management, College of Medicine, National Cheng Kung University. Master.
• 2024 Tzu-Ling Chu. The mixture and mediation effects of phthalates exposures on Alzheimer’s disease through dietary pattern, oxidative stress and steroid hormone. Department of Food Safety / Hygiene and Risk Management, College of Medicine, National Cheng Kung University. Master.
• 2023 Hao-Lun Chang. Integration of food metabolome networks into human physiologically based pharmacokinetic model for investigating the associations between active nutrients and Alzheimer’s disease. Department of Food Safety / Hygiene and Risk Management, College of Medicine, National Cheng Kung University. Master.
• 2023 Chiu-Chin Chen. The study on target and non-target analysis of intentionally and non-intentionally added substances from food contact paper and cardboard materials and application of the threshold of toxicological concern (TTC) concept to the risk assessment. Department of Food Safety / Hygiene and Risk Management, College of Medicine, National Cheng Kung University. Master.
• 2023 Tomohiko Yanagawa. Investigation of microscopic plastics on releasing from food containers and accumulating in freshwater fish in Taiwan. Department of Food Safety / Hygiene and Risk Management, College of Medicine, National Cheng Kung University. Master (Co-advice with Prof. Wei-Hsuan Hsu).
• 2022 Tzu-An Liu. Monitoring of 16 Organophosphate Flame Retardants in Foodstuffs and Dietary Exposure Risk Assessment in the Taiwanese Population. Department of Food Safety / Hygiene and Risk Management, College of Medicine, National Cheng Kung University. Master.
• 2022 Yi-Chin Li. Study on non-target analysis of intentionally and non intentionally added substances from recovery plastic and the feasibility evaluation
  for food contact materials. Department of Food Safety / Hygiene and Risk Management, College of Medicine, National Cheng Kung University. Master (Co-advice with Prof. Ching-Chang Lee).
• 2020 Yi-Wen Huang. The analytical method development to simultaneously measure the 3- and 2-monochloropropane-1,2-diol esters (MCPDEs) in selected processed foods using LC/MS/MS. Department of Food Safety / Hygiene and Risk Management, College of Medicine, National Cheng Kung University. Master (Co-advice with Prof. Ching-Chang Lee).
• 2020 Yu-Hsuan Liu. Characterization and children exposure assessment of organophosphate flame retardants in indoor environment. Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University. Master (Co-advice with Prof. Ching-Chang Lee).

Invited Speech

• Invited Speech in Department of Healthcare Administration, Asia University (2024/12)
• Invited Speech in Institute of Basic Medical Science, National Cheng Kung University (2024/11)
• Invited Speech in School on Mass Spectrometry, National Sun Yat-sen University (2024/07)
• Invited Speech in Kaohsiung Chang Gung Memorial Hospital (2024/04)
• Invited Speech in National Cheng Kung University Hospital (2024/03)
• Invited Speech in Master Degree Program in Toxicology, Kaohsiung Medical University (2023/11)
• Invited Speech in School on Mass Spectrometry, National Sun Yat-sen University (2023/07)
• Invited Speech (Endocrine disruptors) in Chemicals Administration, Ministry of Environment (2023/06) (Taipei, Taiwan)
• Invited Speech (Endocrine disruptors) in Chemicals Administration, Ministry of Environment (2023/03) (Taipei, Taiwan)
• Invited Speech in Environmental Protection Bureau of Taoyuan City Government (2023/10) (Taoyuan, Taiwan)
• Invited Speech in Department of Environmental Science and Engineering, National PingTung University of Science and Technology (2022/12) (PingTung, Taiwan)
• Invited Speech in Department of Public Health, Fu Jen Catholic University (2022/12) (Taipei, Taiwan)
• Invited Speech in College of Engineering and Science, National United University (2022/05) (Miaoli, Taiwan)
• Invited Speech (Dioxin) in Agriculture and Food Agency, Ministry of Agriculture (2022/03) (Taichung, Taiwan)
• Invited Speech in Environmental Protection Bureau of Taoyuan City Government (2022/10) (Taoyuan, Taiwan)
• Invited Speech in Environmental Protection Bureau of Kaohsiung City Government (2022/12) (Kaohsiung, Taiwan)
• Invited Speech in The 5th Cross-Strait Youth Development Forum (2022/11) (Online)

International Conferences

• Wei-Hsiang Chang and Ching-Chang Lee. Dietary exposure to dioxin and dioxin-like compounds in Taiwanese populations with diversified diets. 39th International Symposium on Halogenated Persistent Organic Pollutants – DIOXIN2019, Kyoto, Japan, August 25-30, 2019.
• Jung-Wei Chang, Ching-Chang Lee, Chiao-Yi Cheng, Wei-Hsiang Chang. Temporal trends and spatial distribution of　PCDD/Fs and dioxin-like PCBs in Taiwan foodstuffs. 39th International Symposium on Halogenated Persistent Organic Pollutants – DIOXIN2019, Kyoto, Japan, August 25-30, 2019.
• Wei-Hsiang Chang, Chia-Ding Liao, Guan-Liang Wu, Chung-Feng Hung, Ching-Chang Lee. Dietary exposure and human risk assessment of phthalate esters in processed food. 2019 Conference for Food Hygiene and Inspection Technology, Chiayi, Taiwan, August 21-22, 2019.
• Ching-Chang Lee, Wei-Hsiang Chang and Guan-Liang Wu. Occurrence and profiles of phthalates in processed food from Taiwan and their implications for human exposure. International Association for Food Protection 2019 Annual Meeting (IAFP 2019), Louisville, Kentucky, July 21-24, 2019.
• Wei-Hsiang Chang and Ching-Chang Lee. Estimated daily intake and cumulative risk assessment of perchlorate via diverse foods for Taiwanese populations. International Association for Food Protection 2019 Annual Meeting (IAFP 2019), Louisville, Kentucky, July 21-24, 2019.
• Wei-Hsiang Chang, Hsiu-Ling Chen, Shou-Chun Liu, Ching Chang Lee. Background Monitoring of Nonylphenol and Bisphenol a Levels in Foods Around Taiwan and BPA Migrating Test from Packaging Materials of Coffee Products. International Association for Food Protection 2018 Annual Meeting (IAFP 2018), Salt Lake City, Utah, United State, July 8-11, 2018.
• Ching-Chang Lee and Wei-Hsiang Chang. Occurrence of Perchlorate in Bottled water, Beverage and Tea from Taiwan Market by High Performance Liquid Chromatography–Tandem Mass Spectrometry. International Association for Food Protection 2018 Annual Meeting (IAFP 2018), Salt Lake City, Utah, United State, July 8-11, 2018.
• Hsiu-Ling Chen, Ching Chang Lee, Wei-Hsiang Chang. Integrated Risk Assessment of nonylphenol and bisphenol A through dietary intake in Taiwan population. International Association for Food Protection 2018 Annual Meeting (IAFP 2018), Salt Lake City, Utah, United State, July 8-11, 2018.
• Yu-Ping Fu, Wei-Hsiang Chang, Meng-Hsing Wu, Horng-Yih Ou, Ching-Chang Lee. Urinary perchlorate and thiocyanate are associated with thyroid function in pregnant women. Conference of International Society for Environmental Epidemiology and International Society of Exposure Science－Asia Chapter 2018 (ISEE/ES AC 2018), Taipei, Taiwan, June 21-25, 2018.
• Wei-Hsiang Chang, Ju-Fang Cheng, Wen-Horng Yang, Yuh-Shyan Tsai, Ching-Chang Lee. Concurrent exposure to bisphenol A and nonylphenol associated with the balance of androgen and estrogen in the patients with benign prostatic hyperplasia. 15th Urological Association of Asia Congress (UAA2017), Hong Kong, August 4-6, 2017.
• Chia-Yu Wang, Wei-Hsiang Chang, Ju-Fang Cheng, Wen-Horng Yang, Yuh-Shyan Tsai, Kuan-Hsun Huang, Ching-Chang Lee. Associations between phthalate metabolites and oxidative stress in adult male with benign prostatic hyperplasia. 15th Urological Association of Asia Congress (UAA2017), Hong Kong, August 4-6, 2017.
• Wei-Hsiang Chang, Shou-Chun Liu, Chung-Feng Hung, Yi-Ting Kao, Ya-Chen Hsu,  Shu-Yao Yang, Ching-Chang Lee. Monitoring of bisphenol A and nonylphenol in local and seasonal foods in Taiwan. 2017 3rd International Conference on Food and Agricultural Engineering (ICFAE 2017), Budapest, Hungary, May 10-12, 2017.
• Wei-Hsiang Chang, Shou-Chun Liu, Chung-Feng Hung, Yi-Ting Kao, Ya-Chen Hsu,  Shu-Yao Yang, Ching-Chang Lee. Monitoring of bisphenol A and nonylphenol in local and seasonal foods in Taiwan. 2017 3rd International Conference on Food and Agricultural Engineering (ICFAE 2017), Budapest, Hungary, May 10-12, 2017.
• Shou-Chun Liu, Wei-Hsiang Chang, Chung-Feng Hung, Shu-Yao Yang, Ching-Chang Lee. Background Monitoring of Nonylphenol and Bisphenol A Level in Food around Taiwan and BPA Migrating Test from Packaging Materials of Coffee Products. 2017 conference on Environmental Analytical Chemistry. May 3-4, 2017
• Yu-Ping Fu, Yi-Yun Wu, Wei-Hsiang Chang, Chien-Jung Tien, Ching-Chang Lee. Seasonal and Spatial Variability of Short Chain Chlorinated Paraffin in Sediment and Fish in Taiwan River. 2017 conference on Environmental Analytical Chemistry. May 3-4, 2017
• Wei-Hsiang Chang and Ching-Chang Lee. 2017 Polybrominated diphenyl ether (PBDE) flame retardants: Dietary exposure, human body burden and risk assessment. 2017 Taiwan-Korea Conference of Occupational and environmental Health. February 17, 2017
• Wei-Hsiang Chang, Ju-Fang Cheng, Yin-An Lu, Wen-Horng Yang, Yuh-Shyan Tsai, Ching-Chang Lee. Associations among phthalate exposure, life quality and prostatic disease. Conference of International Society for Environmental Epidemiology and International Society of Exposure Science－Asia Chapter 2016 (ISEE-ISES AC2016), Sapporo, Japan, Jun 26-29, 2016.
• Wei-Hsiang Chang, Meng-Hsing Wu, Hsien-An Pan, Ching-Chang Lee. Phthalate exposures and lifestyle factors on male infertility. The 23rd Pacific Science Congress (PSC-23), Taipei, Taiwan, June 13-17, 2016.
• Ju-Fang Cheng, Yin-An Lu, Wei-Hsiang Chang, Ching-Chang Lee, Associations among phthalate exposure, steroid hormone and prostatic disease in adult man, 2015 International Symposium of Environmental Medicine, Taipei, Taiwan, Oct 24-25, 2015.
• Yin-An Lu, Wei-Hsiang Chang, Wen-Horng Yang, Yuh-Shyan Tsai, TS Tsai; CH Ou; Ching-Chang Lee. Associations among phthalate exposure, steroid hormone and prostatic disease in adult man. 2015 International Conference of Industrial Hygiene & Occupational Medicine, Kaohsiung, Taiwan, April 25-26, 2015.

 National Conferences

• Yi-Wen Huang, Wei-Hsiang Chang, Ching-Chang Lee. Temporal and Spatial Distribution of Nonylphenol and Bisphenol A in sediment from Taiwan principal rivers and influence factors. 2019 conference on Environmental Analytical Chemistry, Taoyuan, Taiwan. May 16-17 2019.
• Sze Ting Choi, Hsiu-Ling Chen, Wei-Hsiang Chang, Ching-Chang Lee. The investigation of dioxins and dioxin-like polychlorobiphenyls in food and exposure assessment in Taiwan air quality maintenance zones. 2019 Annual Food Safety and Analytical Techniques Symposium, Chiayi, Taiwan. Aug 21-22 2019.
• Mei-Chen Cheng, Yu-Wen Chang, Wei-Hsiang Chang, Meng-Hsing Wu, Chen-Hsiang Yu, Ching-Chang Lee. Potential Sources of thyroid disrupting chemicals and its effects of the neonatal development. 2019 Annual joint conferenceof public health, Taipei, Taiwan. Sep 26-28 2019.
• Yu-Hsuan Liu, Wei-Hsiang Chang, Ching-Chang Lee. Analysis of characteristics and fate of organophosphorus flame retardants in indoor environmental using gas chromatography–mass spectrometry. 2019 conference on Environmental Analytical Chemistry, Taoyuan, Taiwan. May 16-17 2019.
• Yu-Wen Chang, Wei-Hsiang Chang, Ching-Chang Lee. Polybrominated diphenyl ethers in sediment from Taiwan principal rivers: levels, spatial and seasonal distribution and influence factors. 2018 conference on Environmental Analytical Chemistry. May 3-4, 2018.
• Guan-Liang Wu, Wei-Hsiang Chang, Ching-Chang Lee. The investigation of the association between phthalate levels in foodstuffs with different packaging materials. 2018 conference on Environmental Analytical Chemistry. May 3-4, 2018.
• Pei-Hsuan Chen, Wei-Hsiang Chang, Ching-Chang Lee. Monitoring and exposure risk assessment of perchlorate in bottled water, tea and tea drinks. 2018 conference on Environmental Analytical Chemistry. May 3-4, 2018.
• Wei-Hsiang Chang, Chun-Ying Lin, Ching-Chang Lee. The emission characteristics of formaldehyde from commercial building materials in Taiwan. Healthy Buildings 2017 Asia, Tainan, Taiwan, Sep 2-5, 2017.
• Wei-Hsiang Chang, Chun-Ying Lin, Ching-Chang Lee. Characteristics of Volatile organic compounds emission from interior decorating materials using chamber models: environment factors, concentrations and risk assessment. Healthy Buildings 2017 Asia, Tainan, Taiwan, Sep 2-5, 2017.